OPKO Health, Inc. (NASDAQ: OPK) is a Healthcare company in the Biotechnology industry. QuoTrend tracks its price, financials, earnings, analyst ratings and insider trades.
| Index | - | P/E | - | EPS (ttm) | -0.10 | Insider Own | - | Shs Outstand | 746.33M | Perf Week | 3.79% |
| Market Cap | 1.02B | Forward P/E | - | EPS next Y | -0.27 | Insider Trans | 0.00% | Shs Float | 323.73M | Perf Month | -1.44% |
| Enterprise Value | 1.11B | PEG | - | EPS next Q | -0.08 | Inst Own | - | Short Float | 4.51% | Perf Quarter | 22.32% |
| Income | -71.98M | P/S | 1.74 | EPS this Y | -123.33% | Inst Trans | - | Short Ratio | 12.23 | Perf Half Y | 11.38% |
| Sales | 587.91M | P/B | 0.87 | EPS next Y | -21.65% | ROA | -3.98% | Short Interest | 33.64M | Perf YTD | 8.73% |
| Book/sh | - | P/C | - | EPS next 5Y | - | ROE | -5.88% | 52W High | 1.74 -20.81% | Perf Year | 7.87% |
| Cash/sh | - | P/FCF | - | EPS past 3/5Y | - | ROIC | -9.07% | 52W Low | 0.98 40.24% | Perf 3Y | -22.16% |
| Dividend Est. | - | EV/EBITDA | 23.97 | Sales past 3/5Y | -15.44% -15.81% | Gross Margin | 30.98% | Volatility | 5.45% 6.43% | Perf 5Y | -60.17% |
| Dividend TTM | - | EV/Sales | 1.89 | EPS Y/Y TTM | -30.38% | Oper. Margin | -25.49% | ATR (14) | 0.09 | Perf 10Y | -86.15% |
| Dividend Ex-Date | - | Quick Ratio | 2.94 | Sales Y/Y TTM | -17.53% | Profit Margin | -12.40% | RSI (14) | 52.90 | Recom | 2.46 |
| Dividend Gr. 3/5Y | - | Current Ratio | 3.35 | EPS Q/Q | 94.74% | SMA20 | 7.07% | Beta | 1.46 | Target Price | 2.87 |
| Payout | 0.00% | Debt/Eq | 0.33 | Sales Q/Q | 4.46% | SMA50 | -0.81% | Rel Volume | 0.76 | Prev Close | 1.37 |
| Employees | 2,275 | LT Debt/Eq | 0.32 | Earnings | Nov 04 | SMA200 | 6.41% | Avg Volume | 3.54M | Price | 1.38 |
| IPO Date | Nov 02, 1995 | Option/Short | No / Yes | EPS/Sales Surpr. | 86.53% 24.59% | Net Debt/EBITDA | 1.97 | Volume | 2,696,633 | Change | 0.73% |
| Date | Action | Analyst | Rating | Target |
|---|---|---|---|---|
| Apr-29-26 | Downgrade | Barrington Research | Outperform → Market Perform | |
| Oct-31-25 | Downgrade | Jefferies | Buy → Hold | $1.60 |
| Jun-29-23 | Upgrade | Barrington Research | Market Perform → Outperform | |
| Dec-15-22 | Reiterated | HC Wainwright & Co. | Buy | $3.00 |
| Jan-24-22 | Downgrade | Barrington Research | Outperform → Market Perform | |
| Mar-02-18 | Downgrade | JP Morgan | Neutral → Underweight | |
| Sep-14-17 | Downgrade | JP Morgan | Overweight → Neutral | |
| Mar-03-15 | Downgrade | Oppenheimer | Outperform → Perform |
OPKO Health, Inc. operates as a healthcare enterprise with a dual focus on diagnostics and pharmaceuticals. Its operations span the United States, Ireland, Chile, Spain, Israel, Mexico, and other international markets. The company's Diagnostics division encompasses BioReference Laboratories, which delivers a comprehensive suite of laboratory testing services. These services are crucial for disease detection, diagnosis, evaluation, monitoring, and treatment, covering areas such as esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare. BioReference serves a diverse client base, including medical practices, clinics, hospitals, employers, and government entities. Additionally, this segment provides a cutting-edge diagnostic instrument system designed for immediate, point-of-care blood test results, alongside its specialized 4Kscore testing for prostate cancer. Within the Pharmaceutical segment, OPKO offers a range of therapeutic products and a robust development pipeline. Key offerings include Rayaldee, indicated for the management of secondary hyperparathyroidism in adults suffering from stage 3 or 4 chronic kidney disease and vitamin D insufficiency. The pipeline features OPK88004, an investigational orally administered selective androgen receptor modulator; OPK88003, a peptide administered once weekly currently in Phase IIb trials for the treatment of type 2 diabetes and obesity; and hGH-CTP, a once-weekly human growth hormone injection that has successfully completed Phase III clinical trials in collaboration with Pfizer, Inc. A core strategy for this segment involves the development and commercialization of proprietary, extended-release versions of existing therapeutic proteins. Furthermore, OPKO Health supplies specialty active pharmaceutical ingredients (APIs) and is involved in the development, manufacturing, marketing, and sale of pharmaceutical, nutraceutical, veterinary, and ophthalmic products. The company also commercializes food supplements and over-the-counter products, produces and sells items primarily within the generics market, and handles the import, marketing, distribution, and sales of pharmaceutical products across various therapeutic areas, including cardiovascular conditions, vaccines, antibiotics, gastro-intestinal ailments, and hormone-related treatments, among others. Its pharmaceutical operations are further bolstered by platforms situated in Ireland, Chile, Spain, and Mexico. Founded in 1991, OPKO Health, Inc. maintains its corporate headquarters in Miami, Florida.
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| Line Item (USD, M) | TTM — | FY 2025 12/31/2025 | FY 2024 12/31/2024 | FY 2023 12/31/2023 | FY 2022 12/31/2022 | FY 2021 12/31/2021 | FY 2020 12/31/2020 | FY 2019 12/31/2019 | FY 2018 12/31/2018 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Total Revenue | 588 | 607 | 713 | — | — | — | — | — | — | |
| Cost of Goods Sold Incl. D&A | 405 | 479 | 402 | — | — | — | — | — | — | |
| Gross Profit | 182 | 128 | 311 | — | — | — | — | — | — | |
| Selling, General and Administrative Excl. Other | 207 | 223 | 304 | — | — | — | — | — | — | |
| Research and Development | 125 | 124 | 105 | — | — | — | — | — | — | |
| Other Operating Expense | 0 | 0 | 54 | — | — | — | — | — | — | |
| Operating Income | -150 | -219 | -152 | — | — | — | — | — | — | |
| Interest Expense | 44 | 108 | 47 | — | — | — | — | — | — | |
| Unusual Expense | — | — | — | — | — | — | — | — | — | |
| Non-Operating Income (Expense) | 115 | 86 | 189 | — | — | — | — | — | — | |
| Net Income Before Taxes | -80 | -241 | -10 | — | — | — | — | — | — | |
| Income Taxes | -7 | -16 | 43 | — | — | — | — | — | — | |
| Consolidated Net Income | -72 | -226 | -53 | — | — | — | — | — | — | |
| Net Income From Continuing Operations | -72 | -226 | -53 | — | — | — | — | — | — | |
| Net Income | -72 | -226 | -53 | — | — | — | — | — | — | |
| EPS (Recurring) | -0.10 | -0.30 | -0.08 | — | — | — | — | — | — | |
| EPS (Basic, Before Extraordinaries) | -0.10 | -0.30 | -0.08 | — | — | — | — | — | — | |
| EPS (Diluted) | -0.10 | -0.30 | -0.08 | — | — | — | — | — | — | |
| EBITDA | 47 | -41 | 135 | — | — | — | — | — | — | |
| Other After Tax Adjustments | — | — | — | — | — | — | — | — | — | |
| Stock Option Compensation Expense | — | — | — | — | — | — | — | — | — | |
| Price To Earnings Ratio | — | — | — | — | — | — | — | — | — | |
| Price To Sales Ratio | 1.77 | 1.56 | 1.43 | — | — | — | — | — | — | |
| Gross Margin | 30.95 | 21.09 | 43.62 | — | — | — | — | — | — | |
| Operating Margin | -25.51 | -36.08 | -21.32 | — | — | — | — | — | — | |
| Net Margin | -12.24 | -37.23 | -7.43 | — | — | — | — | — | — | |
| Shares Outstanding | 755 | 751 | 694 | — | — | — | — | — | — | |
| Market Capitalization | 1,042 | 946 | 1,020 | — | — | — | — | — | — | |
| Operating Lease Expense | — | — | — | — | — | — | — | — | — |
| Insider | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|
| PAGANELLI JOHN A | Director | Mar 20 '26 | Buy | 1.14 | 10,000 | 11,350 | 394,340 | Mar 20 |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 21 '25 | Buy | 1.33 | 580,000 | 768,807 | 216,706,448 | Nov 21 |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 20 '25 | Buy | 1.33 | 580,000 | 771,327 | 216,126,448 | Nov 20 |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 19 '25 | Buy | 1.31 | 580,000 | 759,117 | 215,546,448 | Nov 19 |
| FROST PHILLIP MD ET AL | CEO & Chairman | Nov 18 '25 | Buy | 1.27 | 533,300 | 678,905 | 214,966,448 | Nov 18 |
| FROST PHILLIP MD ET AL | CEO & Chairman | Oct 31 '25 | Buy | 1.42 | 150,000 | 213,435 | 214,386,448 | Oct 31 |
| FROST PHILLIP MD ET AL | CEO & Chairman | Aug 08 '25 | Buy | 1.32 | 675,000 | 891,000 | 214,676,448 | Aug 08 |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 10 '25 | Buy | 1.36 | 125,000 | 169,713 | 214,001,448 | Apr 10 |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 08 '25 | Buy | 1.48 | 125,000 | 184,650 | 213,876,448 | Apr 08 |
| FROST PHILLIP MD ET AL | CEO & Chairman | Apr 01 '25 | Buy | 1.65 | 100,000 | 164,850 | 213,751,448 | Apr 01 |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 28 '25 | Buy | 1.70 | 150,000 | 254,385 | 213,651,448 | Mar 28 |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 17 '25 | Buy | 1.74 | 200,000 | 347,820 | 213,501,448 | Mar 17 |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 04 '25 | Buy | 1.15 | 0 | 0 | 0 | Mar 04 |
| FROST PHILLIP MD ET AL | CEO & Chairman | Mar 03 '25 | Buy | 1.15 | 0 | 0 | 0 | Mar 03 |
| FROST PHILLIP MD ET AL | CEO & Chairman | Feb 28 '25 | Buy | 1.71 | 67,434 | 115,312 | 213,301,448 | Feb 28 |